Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells

Author:

Zhao Guannan12,Wang Qinghui3,Gu Qingqing12,Qiang Wenan45,Wei Jian-Jun4,Dong Peixin67,Watari Hidemichi67,Li Wei3,Yue Junming12

Affiliation:

1. Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, Memphis, USA

2. Center for Cancer Research, University of Tennessee Health Science Center, Memphis, USA

3. Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, USA

4. Department of Pathology, Department of Obstetrics and Gynecology, Northwestern University School of Medicine, Chicago, USA

5. Center for Developmental Therapeutics, Chemistry of Life Processes Institute, Northwestern University, Evanston, USA

6. Department of Women’s Health Educational System, Hokkaido University School of Medicine, Hokkaido University, Sapporo, Japan

7. Department of Gynecology, Hokkaido University School of Medicine, Hokkaido University, Sapporo, Japan

Publisher

Impact Journals, LLC

Subject

Oncology

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