Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients

Author:

Jóri Balazs12,Kamps Rick3,Xanthoulea Sofia1,Delvoux Bert1,Blok Marinus J.2,Van de Vijver Koen K.45,de Koning Bart2,Oei Felicia Trups2,Tops Carli M.6,Speel Ernst J. M.4,Kruitwagen Roy F.1,Gomez-Garcia Encarna B.2,Romano Andrea1

Affiliation:

1. Department of Gynecology and Obstetrics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, The Netherlands

2. Department of Clinical Genetics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, The Netherlands

3. Department of Clinical Genetics, Genomics & Bioinformatics, CARIM - School for Cardiovascular Diseases, Maastricht University Medical Centre, The Netherlands

4. Department of Pathology, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, The Netherlands

5. Current address: Divisions of Diagnostic Oncology & Molecular Pathology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands

6. Department of Clinical Genetics, Leiden University Medical Centre, The Netherlands

Publisher

Impact Journals, LLC

Subject

Oncology

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