The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

Author:

De Wilde Bram12,Beckers Anneleen1,Lindner Sven3,Kristina Althoff3,De Preter Katleen12,Depuydt Pauline12,Mestdagh Pieter12,Sante Tom1,Lefever Steve12,Hertwig Falk45,Peng Zhiyu6,Shi Le-Ming7,Lee Sangkyun8,Vandermarliere Elien910,Martens Lennart910,Menten Björn1,Schramm Alexander3,Fischer Matthias45,Schulte Johannes11,Vandesompele Jo12,Speleman Frank12

Affiliation:

1. Center for Medical Genetics, Ghent University, Ghent, Belgium

2. Cancer Research Institute Ghent, Ghent University, Ghent, Belgium

3. Department of Pediatric Oncology and Hematology, University Children’s Hospital, Essen, Germany

4. Department of Experimental Pediatric Oncology, University Children's Hospital of Cologne, Cologne, Germany

5. Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany

6. BGI-Shenzhen, Bei Shan Industrial Zone, Yantian District, Shenzhen, Guangdong, China

7. Center for Pharmacogenomics and Fudan-Zhangjiang Center for Clinical Genomics, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China

8. Department of Computer Science, Artificial Intelligence Group, TU Dortmund, Dortmund, Germany

9. Medical Biotechnology Center, VIB, Ghent, Belgium

10. Department of Biochemistry, Ghent University, Ghent, Belgium

11. Pediatric Oncology and Hematology, Charité University Medicine, Berlin, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

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