Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC

Author:

Gaykalova Daria A.1,Zizkova Veronika12,Guo Theresa1,Tiscareno Ilse1,Wei Yingying34,Vatapalli Rajita15,Hennessey Patrick T.16,Ahn Julie1,Danilova Ludmila37,Khan Zubair1,Bishop Justin A.18,Silvio Gutkind J.9,Koch Wayne M.1,Westra William H.18,Fertig Elana J.3,Ochs Michael F.310,Califano Joseph A.111

Affiliation:

1. Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

2. Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic

3. Division of Oncology Biostatistics, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

4. Department of Statistics, The Chinese University of Hong Kong, NT, Shatin, Hong Kong

5. Department of Urology, Northwestern University, Chicago, Illinois, USA

6. Department of Otolaryngology, Mid-Michigan Ear Nose and Throat, East Lansing, Michigan, USA

7. Laboratory of Systems Biology and Computational Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia

8. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

9. Department of Pharmacology, UC San Diego Moores Cancer Center, La Jolla, California, USA

10. Department of Mathematics and Statistics, The College of New Jersey, Ewing, New Jersey, USA

11. Department of Surgery, UC San Diego, Moores Cancer Center, La Jolla, California, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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