1. Department of Medical Genetics, Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
2. Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of Cape Town, South Africa
3. Wellcome Trust Centre for Human Genetics and NIHR Comprehensive Biomedical Research Centre, Nuffield Department of Clinical Medicine, Roosevelt Drive, University of Oxford, Oxford OX3 7BN, UK