Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

Author:

Minciacchi Valentina R.1,You Sungyong1,Spinelli Cristiana1,Morley Samantha2,Zandian Mandana1,Aspuria Paul-Joseph3,Cavallini Lorenzo14,Ciardiello Chiara15,Sobreiro Mariana Reis1,Morello Matteo1,Kharmate Geetanjali6,Jang Su Chul7,Kim Dae-Kyum7,Hosseini-Beheshti Elham6,Guns Emma Tomlinson6,Gleave Martin6,Gho Yong Song7,Mathivanan Suresh8,Yang Wei1,Freeman Michael R.12,Di Vizio Dolores12

Affiliation:

1. Division of Cancer Biology and Therapeutics, Departments of Surgery, Biomedical Sciences and Pathology and Laboratory Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

2. The Urological Diseases Research Center, Boston Children's Hospital, Boston, MA, Department of Surgery, Harvard Medical School, Boston, MA, USA

3. Women's Cancer Program, Cedars-Sinai Medical Center, Los Angeles, CA, USA

4. Department of Experimental and Clinical Biomedical Science, University of Florence, Florence, Italy

5. Experimental Pharmacology Unit, Department of Research, IRCCS-Istituto Nazionale Tumori G. Pascale, Naples, Italy

6. Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, BC, Canada

7. Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea

8. Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Australia

Publisher

Impact Journals, LLC

Subject

Oncology

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