The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells-Reference-Cited by-同舟云学术

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

Published:2017-08-07 Issue:41 Volume:8 Page:70736-70751
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

Murakami Yuichi¹²,Sonoda Kahori¹,Abe Hideyuki³,Watari Kosuke¹,Kusakabe Daiki¹⁴,Azuma Koichi⁵,Kawahara Akihiko³,Akiba Jun³,Oneyama Chitose⁶,Pachter Jonathan A.⁷,Sakai Kazuko⁸,Nishio Kazuto⁸,Kuwano Michihiko²,Ono Mayumi¹

Affiliation:

1. Department of Pharmaceutical Oncology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan

2. Cancer Translational Research Center, St. Mary’s Institute of Health Sciences, Fukuoka, Japan

3. Department of Diagnostic Pathology, Kurume University Hospital, Fukuoka, Japan

4. Physical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan

5. Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan

6. Division of Microbiology and Oncology, Aichi Cancer Center Research Institute, Nagoya, Japan

7. Verastem Inc., Cambridge, MA, USA

8. Department of Genome Biology, Kinki University Faculty of Medicine, Osaka, Japan

Publisher

Impact Journals, LLC

Subject

Oncology

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