The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

Author:

Giordani Giorgia12,Barraco Marilena13,Giangrande Angela4,Martinelli Giovanni5,Guadagnuolo Viviana5,Simonetti Giorgia5,Perini Giovanni16,Bernardoni Roberto16

Affiliation:

1. Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Bologna, Italy

2. Present address: Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK

3. Present address: Institute of Hematology, “L e A Seràgnoli”, S. Orsola-Malpighi Hospital, Bologna, Italy

4. Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP 67404 Illkirch, France

5. Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Institute of Hematology “L. e A. Seràgnoli”, University of Bologna, Bologna, Italy

6. Health Sciences and Technology - Interdepartmental Center for Industrial Research (HST-ICIR), University of Bologna, Ozzano Emilia, Italy

Publisher

Impact Journals, LLC

Subject

Oncology

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