STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation

Author:

Singh Mohini12,Garg Neha13,Venugopal Chitra13,Hallett Robin4,Tokar Tomas5,McFarlane Nicole13,Mahendram Sujeivan13,Bakhshinyan David12,Manoranjan Branavan162,Vora Parvez13,Qazi Maleeha12,Arpin Carolynn C.7,Page Brent7,Haftchenary Sina7,Rosa David A.7,Lai Ping-Shan7,Gómez-Biagi Rodolfo F.7,Ali Ahmed M.8,Lewis Andrew7,Geletu Mulu7,Murty Naresh K.3,Hassell John A.1429,Jurisica Igor51011,Gunning Patrick T.7,Singh Sheila K.123

Affiliation:

1. McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, Ontario, Canada

2. Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

3. Departments of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada

4. McMaster Centre for Functional Genomics, McMaster University, Hamilton, Ontario, Canada

5. Princess Margaret Cancer Centre, University Health Network, IBM Life Sciences Discovery Centre, Toronto Medical Discovery Tower, Toronto, Ontario, Canada

6. Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

7. Department of Chemistry, University of Toronto, Mississauga, ON, Canada

8. Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt

9. Departments of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

10. TECHNA Institute for the Advancement of Technology for Health, UHN and University of Toronto, Toronto, Ontario, Canada

11. Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Ontario, Canada

Publisher

Impact Journals, LLC

Subject

Oncology

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