Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancerin vivoandin vitrothrough elevating p21 and ROS levels-Reference-Cited by-同舟云学术

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancerin vivoandin vitrothrough elevating p21 and ROS levels

Published:2014-06-29 Issue:12 Volume:5 Page:4567-4578
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

Popovics Petra¹²³,Schally Andrew V.¹⁴⁵⁶,Szalontay Luca¹,Block Norman L.¹⁴⁵,Rick Ferenc G.¹⁷

Affiliation:

1. Veterans Affairs Medical Center and South Florida Veterans Affairs Foundation for Research and Education, Miami, FL

2. Division of Cardiovascular Diseases, Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL

3. Department of Medicine III, Medical Faculty Carl Gustav Carus, Dresden, Germany

4. Department of Pathology, University of Miami, Miller School of Medicine, Miami, FL

5. Division of Hematology/Oncology, Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL

6. Division of Endocrinology, Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL

7. Department of Urology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL

Publisher

Impact Journals, LLC

Subject

Oncology

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1. Biopolymer and Biomaterial Conjugated Iron Oxide Nanomaterials as Prostate Cancer Theranostic Agents: A Comprehensive Review;Symmetry;2021-05-31

2. Dissecting the Hormonal Signaling Landscape in Castration-Resistant Prostate Cancer;Cells;2021-05-07

3. Gonadotropin-Releasing Hormone Receptors in Prostate Cancer: Molecular Aspects and Biological Functions;International Journal of Molecular Sciences;2020-12-14

4. Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer;Oncology Letters;2020-11-19

5. Novel Crizotinib–GnRH conjugates revealed the significance of lysosomal trapping in GnRH-based drug delivery systems;International Journal of Molecular Sciences;2019-11-08