TKI sensitivity patterns of novel kinase-domain mutations suggest therapeutic opportunities for patients with resistant ALK+ tumors

Author:

Amin Amit Dipak1,Li Lingxiao1,Rajan Soumya S.2,Gokhale Vijay34,Groysman Matthew J.5,Pongtornpipat Praechompoo3,Tapia Edgar O.6,Wang Mengdie6,Schatz Jonathan H.1

Affiliation:

1. Department of Medicine, Division of Hematology-Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA

2. Sheila and David Fuente Graduate Program in Cancer Biology, University of Miami Miller School of Medicine, Miami, FL, USA

3. BIO5 Institute, University of Arizona, Tucson, AZ, USA

4. Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ, USA

5. Undergraduate Biology Research Program, University of Arizona, Tucson, AZ, USA

6. Cancer Biology Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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