Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma

Author:

Braig Friederike1,Voigtlaender Minna1,Schieferdecker Aneta1,Busch Chia-Jung2,Laban Simon23,Grob Tobias4,Kriegs Malte5,Knecht Rainald2,Bokemeyer Carsten1,Binder Mascha1

Affiliation:

1. Department of Oncology and Hematology with Sections Bone Marrow Transplant and Pneumology, Hubertus Wald Tumorzentrum / University Cancer Center Hamburg, University Medical Center Hamburg, Hamburg, Germany

2. Department of Otorhinolaryngology, Head and Neck Cancer Center of The University Cancer Center Hamburg, University Medical Center Hamburg, Hamburg, Germany

3. Department of Otorhinolaryngology and Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany

4. Department of Pathology, University Medical Center Hamburg, Hamburg, Germany

5. Laboratory for Radiobiology and Experimental Radiooncology, Head and Neck Cancer Center of The University Cancer Center Hamburg, University Medical Center Hamburg, Hamburg, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

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