MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models-Reference-Cited by-同舟云学术

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MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models

Published:2018-01-22 Issue:14 Volume:9 Page:11592-11603
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

Vena Francesca¹,Jia Ruochen¹,Esfandiari Arman¹,Garcia-Gomez Juan J.¹,Rodriguez-Justo Manuel²,Ma Jianguo³,Syed Sakeena³,Crowley Lindsey³,Elenbaas Brian³,Goodstal Samantha³,Hartley John A.¹,Hochhauser Daniel¹

Affiliation:

1. Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O’Gorman Building, University College London, London WC1E 6DD, UK

2. Department of Research Pathology, UCL Cancer Institute, London EC1M6BQ, UK

3. EMD Serono Research and Development Institute, Billerica 01821, MA, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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2. Poly (ADP-ribose) polymerase inhibitor therapy and mechanisms of resistance in epithelial ovarian cancer;Frontiers in Oncology;2024-07-29

3. Ovarian cancer: Diagnosis and treatment strategies (Review);Oncology Letters;2024-07-18

4. Oncogenic Pathways and Targeted Therapies in Ovarian Cancer;Biomolecules;2024-05-15

5. MEK Inhibition Enhances the Antitumor Effect of Radiotherapy in NF1-Deficient Glioblastoma;Molecular Cancer Therapeutics;2024-05-07

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