Whole genome sequence analysis links chromothripsis to EGFR, MDM2, MDM4, and CDK4 amplification in glioblastoma-Reference-Cited by-同舟云学术

Whole genome sequence analysis links chromothripsis to EGFR, MDM2, MDM4, and CDK4 amplification in glioblastoma

Published:2015-07-31 Issue:7 Volume:2 Page:618-628
ISSN:2331-4737
Container-title:Oncoscience
language:en
Short-container-title:Oncoscience

Author:

Furgason John M.¹,Koncar Robert F.¹,Michelhaugh Sharon K.²,Sarkar Fazlul H.³,Mittal Sandeep²,Sloan Andrew E.⁴⁵,Barnholtz-Sloan Jill S.⁴,Bahassi El Mustapha¹

Affiliation:

1. Department of Internal Medicine; Division of Hematology/Oncology and UC Brain Tumor Center, University of Cincinnati, Cincinnati OH, USA

2. Department of Neurosurgery, Wayne State University and Karmanos Cancer Institute, Detroit, MI, USA

3. Department of Pathology, Wayne State University College of Medicine, Detroit, MI, USA

4. Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA

5. Department of Neurological Surgery, University Hospitals Case Medical Center, Cleveland, Ohio, USA

Publisher

Impact Journals, LLC

Subject

Cancer Research,Oncology

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3. Chromothripsis is rare in IDH-mutant gliomas compared to IDH-wild-type glioblastomas whereas whole-genome duplication is equally frequent in both tumor types;Neuro-Oncology Advances;2024-01-01

4. Comprehensive Molecular Genetic Analysis in Glioma Patients by Next Generation Sequencing;Brain Tumor Research and Treatment;2024

5. Pan-cancer analysis of chromothripsis-related gene expression patterns indicates an association with tumor immune and therapeutic agent responses;Frontiers in Oncology;2023-01-24