Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration

Author:

Zhang Wenjing12,Cheng Wen3,Parlato Rosanna45,Guo Xiaosun1,Cui Xiaopei2,Dai Chaochao12,Xu Lei6,Zhu Jiankang7,Zhu Min8,Luo Kun9,Zhang Wencheng3,Dong Bo10,Wang Jianli111,Jiang Fan12

Affiliation:

1. Department of Physiology and Pathophysiology, School of Basic Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, China

2. Key Laboratory of Cardiovascular Proteomics of Shandong Province, Qilu Hospital of Shandong University, Jinan, China

3. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, and The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China

4. Institute of Applied Physiology, University of Ulm, Ulm, Germany

5. Institute of Anatomy and Cell Biology, University of Heidelberg, Heidelberg, Germany

6. Department of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

7. Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University, Jinan, China

8. Department of Transplant Surgery, Qilu Hospital of Shandong University, Jinan, China

9. Department of Vascular Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China

10. Department of Cardiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China

11. Current address: Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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