Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3
Author:
Affiliation:
1. Discovery Oncology, Roche Research Center, Hoffmann-La Roche Inc., Nutley, NJ 07110, USA
Publisher
Impact Journals, LLC
Subject
Cell Biology,Ageing
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Senescent cells limit p53 activity via multiple mechanisms to remain viable;Nature Communications;2022-06-28
2. A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2;International Journal of Molecular Sciences;2021-12-21
3. Crosstalk between Noxa, Bcl-2, and ceramide in mediating p53-dependent apoptosis in Molt-4 human T-cell leukemia;Molecular and Cellular Biochemistry;2020-08-07
4. Senolytics Target Senescent Cells and Improve Aging and Age-Related Diseases;Healthy Ageing and Longevity;2020
5. Voltage‐gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation;FEBS Letters;2019-11-12
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