1. National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, Taiwan
2. Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, Taiwan
3. Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan
4. Orthopaedics Medicine, Miaoli General Hospital, Miaoli city, Taiwan
5. Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan