Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency

Author:

Ohmine Seiga1,Squillace Karen A.1,Hartjes Katherine A.1,Deeds Michael C.2,Armstrong Adam S.2,Thatava Tayaramma1,Sakuma Toshie1,Terzic Andre3,Kudva Yogish24,Ikeda Yasuhiro1

Affiliation:

1. Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA

2. Cell Therapy, Department of Laboratory Medicine/Pathology, Mayo Clinic, Rochester, MN 55905, USA

3. Robert and Arlene Kogod Center on Aging, Marriott Heart Disease Research Program, Division of Cardiovascular Diseases, Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics, and Medical Genetics, Mayo Clinic, Rochester, MN 55905, USA

4. Division of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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