Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

Author:

Fiorillo Marco123,Lamb Rebecca12,Tanowitz Herbert B.4,Cappello Anna Rita3,Martinez-Outschoorn Ubaldo E.5,Sotgia Federica6,Lisanti Michael P.12

Affiliation:

1. The Breast Cancer Now Research Unit, Institute of Cancer Sciences, Cancer Research UK Manchester Institute, University of Manchester, Manchester, UK

2. The Manchester Centre for Cellular Metabolism (MCCM), Institute of Cancer Sciences, Cancer Research UK Manchester Institute, University of Manchester, Manchester, UK

3. The Department of Pharmacy, Health and Nutritional Sciences, The University of Calabria, Cosenza, Italy

4. Departments of Pathology and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA

5. The Sidney Kimmel Cancer Center, Philadelphia, PA 19107, USA

6. School of Environment & Life Sciences, Cockcroft Building, University of Salford, Salford, UK

Publisher

Impact Journals, LLC

Subject

Cell Biology,Ageing

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