Author:
Malkhasyan I.E.,Sisakian H.S.,Hovhannisyan M.R.,Vardanyan A.K.,Avetsiyan Q.A.,Martirsyan G.E.,Terteryan A.M.,Hovakimyan M.H.
Abstract
Pulmonary embolism (PE) is a condition characterized by high in-hospital mortality rates and often goes undiagnosed. Despite advancements in both treatment and diagnosis, many patients still receive unclear, evidence-directed treatment in both hospital and outpatient settings. Although significant progress has been made in managing acute pulmonary embolism, the risk of acute clinical deterioration and mortality remains high.
Data collected from Yerevan State Medical University Hospital in Armenia on acute pulmonary embolism presentations, along with a two-year follow-up, were used to assess outcomes and treatment modalities.
Current clinical guidelines recommend anticoagulation treatment for low- and intermediate-risk PE patients, while systemic thrombolysis or thrombectomy is recommended for high-risk PE patients. Despite adherence to guideline-based treatment, high-risk PE patients with advanced right ventricular failure and hemodynamic instability continue to experience high in-hospital mortality rates (33.3%). Early identification of high-risk patients and tailored treatment approaches may help reduce in-hospital mortality. Further studies are necessary to refine treatment strategies for such patients.
Publisher
Yerevan State Medical University