ՍՈՒՐ ԹՈՔԱՅԻՆ ԷՄԲՈԼԻԱՅՈՎ ՀԻՎԱՆԴՆԵՐԻ ԿԼԻՆԻԿԱԿԱՆ ԵՎ ԲՈՒԺՄԱՆ ԳՆԱՀԱՏՈՒՄԸ։ ԵՐԿՈՒ ՏԱՐՎԱ ԴԻՏԱՐԿՈՒՄ ՀԵՐԱՑԻ ԹԻՎ 1 ՀԻՎԱՆԴԱՆՈՑԱՅԻՆ ՀԱՄԱԼԻՐՈՒՄ

Author:

Malkhasyan I.E.,Sisakian H.S.,Hovhannisyan M.R.,Vardanyan A.K.,Avetsiyan Q.A.,Martirsyan G.E.,Terteryan A.M.,Hovakimyan M.H.

Abstract

Pulmonary embolism (PE) is a condition characterized by high in-hospital mortality rates and often goes undiagnosed. Despite advancements in both treatment and diagnosis, many patients still receive unclear, evidence-directed treatment in both hospital and outpatient settings. Although significant progress has been made in managing acute pulmonary embolism, the risk of acute clinical deterioration and mortality remains high. Data collected from Yerevan State Medical University Hospital in Armenia on acute pulmonary embolism presentations, along with a two-year follow-up, were used to assess outcomes and treatment modalities. Current clinical guidelines recommend anticoagulation treatment for low- and intermediate-risk PE patients, while systemic thrombolysis or thrombectomy is recommended for high-risk PE patients. Despite adherence to guideline-based treatment, high-risk PE patients with advanced right ventricular failure and hemodynamic instability continue to experience high in-hospital mortality rates (33.3%). Early identification of high-risk patients and tailored treatment approaches may help reduce in-hospital mortality. Further studies are necessary to refine treatment strategies for such patients.

Publisher

Yerevan State Medical University

Reference8 articles.

1. Andersson T., Söderberg S. Incidence of acute pulmonary embolism, related comorbidities, and survival; analysis of a Swedish national cohort. BMC Cardiovasc Disord., 2017 Jun 14; 17(1):155. doi: 10.1186/s12872-017-0587-1  PMCID: PMC5471722 PMID: 28615009

2. Jiménez D.,  Lobo J.L., Barrios D., Prandoni P., Yusen R.D. Risk stratification of patients with acute symptomatic pulmonary embolism. Chest, 2016 Jun PMID: 26768476 DOI: 10.1007/s11739-015-1388-0

3. Konstantinides S.V., Meyer G., Becattini C., Bueno H., Geersing G., Harjola V., Huisman M.V., Humbert M., Jennings C.S., Jiménez D., Kucher N., Lang I.M., Lankeit M., Lorusso R., Mazzolai L., Meneveau N., Áinle F.N., Prandoni P., Pruszczyk P., Righini M., Torbicki A., Van Belle E., Zamorano J.L. ESC Scientific Document Group 2019, ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS), European Heart Journal, V. 41, Issue 4, 21 January 2020, pp. 543–603, PMID: 3150442 DOI: 10.1093/eurheartj/ehz405,31 August 2019  https://doi.org/10.1093/eurheartj/ehz405

4. Kucher N., Rossi E., De Rosa M., Goldhaber S.Z. Massive pulmonary embolism Circulation 2006, PMID: 16432055 DOI: 10.1161/CIRCULATIONAHA.105.592592

5. Natanzon S.S., Fardman A., Chernomordik F., Mazin I., Herscovici R., Goitein O., Ben-Zekry S., Younis A., Grupper A., Matetzky S., Roy Beigel, PESI score for predicting clinical outcomes in PE patients with right ventricular involvement Heart Vessels 2022 Mar , PMID: 34420078 DOI: 10.1007/s00380-021-01924-w

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