Case Report: Amphotericin B and Mefloquine as a Salvage Treatment of Alveolar Echinococcosis

Author:

Jelicic Karlo1,Papic Neven12,Viskovic Klaudija13,Vince Adriana12

Affiliation:

1. University Hospital for Infectious Diseases Zagreb, Zagreb, Croatia;

2. School of Medicine, University of Zagreb, Zagreb, Croatia;

3. Faculty of Health Studies, University of Rijeka, Rijeka, Croatia

Abstract

ABSTRACT. Alveolar echinococcosis is an emerging zoonotic disease caused by the parasite Echinococcus multilocularis. Most patients are diagnosed at a late stage, when lifelong treatment with benzimidazoles is required to stop disease progression. However, for patients who do not tolerate benzimidazole therapy, there are no alternatives. Here, we present a patient with advanced alveolar echinococcosis who was successfully treated with amphotericin B deoxycholate and mefloquine as a rescue therapy after he developed albendazole intolerance.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference15 articles.

1. Echinococcosis: A review;Moro,2009

2. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans;Brunetti,2010

3. Evaluation of treatment and long-term follow-up in patients with hepatic alveolar echinococcosis;Kadry,2005

4. Echinococcosis: Advances in the 21st century;Wen,2019

5. Alveolar echinococcosis: from a deadly disease to a well-controlled infection. Relative survival and economic analysis in Switzerland over the last 35 years;Torgerson,2008

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Novel Chemotherapeutical Approaches Against Echinococcosis: A Swiss Perspective;Parasitology Research Monographs;2024

2. Albendazole/amphotericin-B;Reactions Weekly;2023-04-22

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