Case Report: Role of Point-of-Care Ultrasound in the Diagnosis of Bacillary Angiomatosis

Author:

Stroffolini Giacomo1,Rambiki Kelvin2,Wallrauch Claudia2,Tomoka Tamiwe3,Brunetti Enrico4,Heller Tom25

Affiliation:

1. Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy;

2. Lighthouse Clinic Trust, Lilongwe, Malawi;

3. Pathology Lab, University of North Carolina School of Medicine, Lilongwe, Malawi;

4. Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Immunology and Infectious Diseases, IRCCS San Matteo Hospital Foundation, Pavia, Italy;

5. International Training and Education Center for Health, University of Washington, Seattle, Washington

Abstract

ABSTRACT. Clinical skin manifestations are commonly seen in resource-limited settings, but they are frequently misdiagnosed due to the lack of microbiological tests with ensuing stigma and long-term disability. The adoption of portable ultrasound devices, which extend physical examination in the hands of trained clinicians, has partially improved the situation. Specific protocols, such as focused assessment with sonography for HIV-associated tuberculosis (FASH), have led to simplified diagnostic pathways. Here we describe a case of bacillary angiomatosis in a patient with advanced HIV disease presenting with subacute unusual cutaneous lesions. The patient also presented with significant weight loss, anemia, and prostration. Highly sensitive rapid tests for tuberculosis and cryptococcosis were negative, and CD4 count was very low. Ultrasound scanning (US) and biopsy of the cutaneous lesions finally led to diagnosis and treatment. This report illustrates the benefits of integrating ultrasound-based protocols with clinical skills, as the diagnosis was suspected based on clinical presentation and US and confirmed by pathology. The importance of adoption of US protocols by infectious diseases clinicians is discussed.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference14 articles.

1. Sound around the world: ultrasound for tropical diseases;Kaminstein,2019

2. Point-of-care ultrasound assessment of tropical infectious diseases – a review of applications and perspectives;Bélard,2016

3. Focused assessment with sonography for HIV-associated tuberculosis (FASH): a short protocol and a pictorial review;Heller,2012

4. Abdominal ultrasound for the diagnosis of tuberculosis among human immunodeficiency virus-positive inpatients with World Health Organization danger signs;Griesel,2019

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