Case Report: Leptospirosis by Wild Rat Bite in Winter in Tokyo Metropolitan Area, Japan

Author:

Suzuki Tetsuya12,Morioka Shinichiro12,Kikuchi Tatsuya1,Sato Lubna1,Nomoto Hidetoshi12,Yamamoto Kei1,Koizumi Nobuo3,Hayakawa Kayoko1,Kutsuna Satoshi14,Ohmagari Norio12

Affiliation:

1. Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan;

2. Emerging and Re-emerging Infectious Diseases, Graduate School of Medicine, Tohoku University, Sendai, Japan;

3. Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan;

4. Department of Infection Control, Graduate School of Medicine/Faculty of Medicine, Osaka University, Osaka, Japan

Abstract

ABSTRACT. We report a case of leptospirosis in Tokyo in winter due to a rat bite, an uncommon cause of Leptospira infection. In Japan, many cases due to exposure to fresh water have been reported from domestic southwest islands in summer. However, a previous report on leptospirosis in Tokyo documented several cases occurring in winter. The main route of infection in the Tokyo metropolitan area during winter was attributed to the increased chance of direct rat exposure. Rapid and feasible diagnostic methods are needed to elucidate its epidemiology and provide prompt treatment.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference9 articles.

1. Patterns in Leptospira shedding in Norway rats (Rattus norvegicus) from Brazilian slum communities at high risk of disease transmission;Costa,2015

2. Leptospira spp. in the oral cavity of urban brown rats (Rattus norvegicus) from Vancouver, Canada-implications for rat-rat and rat-human transmission;Donovan,2018

3. Rat-bite acquired leptospirosis;Luzzi,1987

4. Severe leptospirosis after rat bite: a case report;Faggion Vinholo,2020

5. Global morbidity and mortality of leptospirosis: a systematic review;Costa,2015

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