Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria-Reference-Cited by-同舟云学术

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria

Published:2017-08-02 Issue:2 Volume:97 Page:514-525
ISSN:0002-9637
Container-title:The American Journal of Tropical Medicine and Hygiene
language:en
Short-container-title:

Author:

Supan Christian¹²,Walsh Douglas S.³,Lell Bertrand¹²,Kombila Maryvonne⁴,Polhemus Mark E.³,Ospina Salazar Carmen L.¹²,Kremsner Peter G.¹²,Cantalloube Cathy⁵,Otsula Nekoye³,Djeriou Elhadj⁵,Apollo Duncan³,Waitumbi John³,Ogutu Bernhards³,Mombo-Ngoma Ghyslain¹²,Held Jana¹²

Affiliation:

1. Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany;

2. Centre de Recherches Médicales de Lambaréné, Hôpital Albert Schweitzer, Lambaréné, Gabon;

3. Walter Reed Project (Kisumu), U.S. Army Medical Research Unit (USAMRU)-Kenya, Kenya Medical Research Institute, Nairobi, Kenya

4. Département de Parasitologie-Mycologie, Faculté de Médecine, Université des Sciences de la Santé, Libreville, Gabon;

5. Sanofi-Aventis, Paris, France;

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference17 articles.

1. Spread of artemisinin resistance in malaria;Hawkes;N Engl J Med,2014

2. The antimalarial ferroquine: from bench to clinic;Biot;Parasite,2011

3. In vitro susceptibility to a new antimalarial organometallic analogue, ferroquine, of Plasmodium falciparum isolates from the Haut-Ogooue region of Gabon;Atteke;J Antimicrob Chemother,2003

4. In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border;Barends;Malar J,2007

5. Inhibitory activity of ferroquine, versus chloroquine, against western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay;Eyase;Am J Trop Med Hyg,2011

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