Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers

Author:

Rueangweerayut Ronnatrai1,Bancone Germana2,Harrell Emma J.3,Beelen Andrew P.4,Kongpatanakul Supornchai5,Möhrle Jörg J.6,Rousell Vicki3,Mohamed Khadeeja3,Qureshi Ammar3,Narayan Sushma3,Yubon Nushara7,Miller Ann8,Nosten François H.2,Luzzatto Lucio910,Duparc Stephan6,Kleim Jörg-Peter3,Green Justin A.3

Affiliation:

1. Department of Internal Medicine, Mae Sot General Hospital, Mae Sot, Thailand;

2. Shoklo Malaria Research Unit, Mahidol–Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand;

3. GlaxoSmithKline Research and Development Ltd., Uxbridge, United Kingdom;

4. GlaxoSmithKline, Research Triangle Park, North Carolina;

5. Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand;

6. Medicines for Malaria Venture, Geneva, Switzerland;

7. GlaxoSmithKline, Bangkok, Thailand;

8. GlaxoSmithKline, King of Prussia, Pennsylvania;

9. Department of Hematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania

10. Istituto Toscano Tumori, Florence, Italy;

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

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