Factors Associated with Mortality among Hospitalized Patients with COVID-19: A Retrospective Cohort Study

Author:

Martins-Filho Paulo Ricardo1,Antunes de Souza Araújo Adriano1,Pereira Luciana Xavier2,Quintans-Júnior Lucindo José1,de Souza Barboza Waneska3,Cavalcante Taise Ferreira3,Feitosa de Souza Mércia14,de Oliveira Góes Marco Aurélio14,Santos Victor Santana2

Affiliation:

1. 1Federal University of Sergipe, Sao Cristovao, Brazil;

2. 2Federal University of Alagoas, Arapiraca, Brazil;

3. 3Aracaju City Hall, Municipal Health Secretariat, Aracaju, Brazil;

4. 4Government of Sergipe State, State Health Secretariat, Aracaju, Brazil

Abstract

ABSTRACTInformation on the risk factors for COVID-19 mortality in low- and middle-income countries is still scarce. In this retrospective cohort study, we analyzed the factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil. Logistic regression was used to identify factors independently associated with mortality, including gender, age, and the presence of underlying medical conditions. A total of 1,207 patients were included in the analysis, and a 1.5-fold increase in COVID-19 mortality was found among patients aged > 65 years with hypertension and diabetes (odds ratio [OR]: 1.50, 95% CI: 1.02–2.19). Moreover, infectious disease (OR: 4.31, 95% CI: 1.39–13.39), kidney disease (OR: 2.59, 95% CI: 1.27–5.27), and heart disease (OR: 2.00, 95% CI: 1.31–3.04) were also predictive for COVID-19 in-hospital death. This large cohort provides important data on potential factors associated with COVID-19 mortality in Brazil.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

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