Case Report: Fatal Rickettsiosis in Pregnancy

Author:

Ponce Nájera Eduardo12,Lozano Lazcano Valeria12,Ploneda González César3,Montoya Hinojosa Marcela1,González Oropeza Diego12

Affiliation:

1. Hospital Regional Materno Infantil del Estado de Nuevo León, Nuevo León, Mexico;

2. Escuela de Medicina y Ciencias de la Salud Tecnológico de Monterrey, Nuevo León, Mexico;

3. Hospital Metropolitano “Dr. Bernardo Sepúlveda’’ del Estado de Nuevo León, Nuevo León, Mexico

Abstract

ABSTRACT. Rocky Mountain spotted fever (RMSF) is a tick-borne infection caused by Rickettsia rickettsii. We present a series of two cases of pregnant patients who showed up at the emergency room of a hospital in Nuevo León, Mexico. Both patients lived in environments where R. rickettsii is endemic and they presented with several days of symptoms, including fever. Both patients developed a rash and had stillbirths during their hospital stay. Treatment with doxycycline was delayed, with fatal results in both patients. Diagnosis of RMSF was confirmed via polymerase chain reaction assay postmortem. The need to link epidemiological clues with clinical data is critical in the diagnosis and early treatment of RMSF to prevent maternal deaths.

Publisher

American Society of Tropical Medicine and Hygiene

Reference23 articles.

1. Obstetric Catastrophes: A Clinical Guide,2021

2. Emerging and re-emerging rickettsial infections;Adem,2019

3. Epidemiology and clinical features of Rocky Mountain spotted fever from enhanced surveillance, Sonora, Mexico: 2015–2018;Álvarez-López,2021

4. Pathogenesis of rickettsial diseases: pathogenic and immune mechanisms of an endotheliotropic infection;Sahni,2019

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