Sentinel Lymph Node Evaluation in Squamous Cell Carcinoma of the Head and Neck-Reference-Cited by-同舟云学术

Sentinel Lymph Node Evaluation in Squamous Cell Carcinoma of the Head and Neck

Published:2001-09 Issue:3 Volume:125 Page:221-226
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Stoeckli Sandro J.¹²,Steinert H.¹³,Pfaltz M.¹⁴,Schmid Stephan¹²

Affiliation:

1. Zurich, Switzerland

2. Clinic of Otorhinolaryngology—Head and Neck Surgery, University Hospital Zurich.

3. Division of Nuclear Medicine, University Hospital Zurich.

4. Department of Pathology, University Hospital Zurich.

Abstract

OBJECTIVE: The aim of our study was to assess the feasibility of sentinel lymph node (SLN) radiolocalization in N0 neck in squamous cell head and neck carcinoma and its predictive value for occult metastasis. Study Design: Nineteen patients of an open prospective trial. SETTING: After peritumoral injection of a 99m Tc labeled radiocolloid, the SLN was localized preoperatively by lymphoscintigraphy and intraoperatively through the intact skin by a hand-held gamma-probe. The histology of the SLN and the nodes of the elective neck dissection were compared. RESULTS: Localization of the SLN by lymphoscintigraphy was possible in 18 of 19, and with the handheld gamma-probe in all 19 patients. Six SLN revealed occult metastatic disease. No skip metastasis were found in the 13 neck specimen with negative SLN. CONCLUSION: SLN evaluation in N0 neck in squamous cell carcinoma of the head and neck is accurately feasible and seems to adequately predict the presence of occult metastasis.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1067/mhn.2001.118074

Reference9 articles.

1. The Incidence of Micrometastases in Neck Dissection Specimens Obtained From Elective Neck Dissections

2. Rationale for elective modified neck dissection

3. Technical Details of Intraoperative Lymphatic Mapping for Early Stage Melanoma

4. Sentinel lymph node status as an indicator of the presence of metastatic melanoma in regional lymph nodes

5. Intraoperative Radiolymphoscintigraphy Improves Sentinel Lymph Node Identification for Patients with Melanoma

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