Redox Potentials of Blood Serum in Patients with Acute Cerebral Pathology

Abstract

According to B. Nordenstrom's concept, homeostasis is controlled by biologically closed electrical circuits in the organism. Therefore, a wide application of implanted platinum electrodes in medicine for diagnostics and treatment is not surprising. Open circuit potentials of platinum electrodes in biological media, termed redox potentials, reflect the level of pro- and antioxidant activities in the organism. The dynamics of redox shifts towards negative potentials in patients with acute cerebral pathology as a result of the treatment by hyperbaric oxygenation was investigated. It was suggested that an increase in antioxidant activity occurs. Thus, redox potential measurements can be used to elucidate certain mechanisms of the effect of hyperbaric oxygenation procedure in patients with acute cerebral pathology. Correlation between redox values and toxicity or quantity of "middle molecule" was found.