Selective Detection of Creatinine Using Enzymatic Route for Diagnosis of Chronic Kidney Diseases

Abstract

Chronic kidney diseases are becoming most common health issues due to growing age, hypertension and high cholesterol that causes poor kidney functioning and eventually death also. Creatinine is a serum present in blood and urine that measures the kidney functioning. We have designed a highly sensitive and precise sensor for the creatinine sensing. Eu—doping in tin oxide (SnO2) is used to enhance the sensitivity and limit of detection. A precise working range of this sensor is also found by the calibration curve between FWHM and figure of Merit with respect to the concentration of creatinine. A selectivity experiment with enzymatic route is followed to make this sensor selective for creatinine only. This sensor may find plentiful deliberation in the field of sensing and mainly in medical applications.