Au-wrapped CuS-Interlaced Chain Structure for Ultrafast Response and High Sensitive Non-Enzymatic Glucose Sensor

Abstract

We report the fabrication and testing of ultrafast response nonenzymatic glucose sensor based on the use of interlaced chain structure Au@CuS nanomaterial. The new Au@CuS nanomaterial was synthesized by a facile solvothermal method from L-cysteine、Cu(NO3)2·3H2O and Au Seeds without using additional surfactants or templates. The combination of Au and CuS solves the problems of poor electrical conductivity of CuS and the susceptibility of Au to toxicity, while the interlaced chain structure exposes more active sites to facilitate the diffusion of glucose molecules with a low resistance to increase the inter-electron transfer rate. The non-enzymatic Au@CuS-based glucose sensor showed a wide linear range with excellent sensitivity (5817.37 and 3629.78 μA mM−1cm−2), ultrafast response time (<0.1 s), excellent selectivity and outstanding long-term stability. Further, the designed glucose sensor was used to determine glucose in human blood serum sample with satisfactory result.