Features of myocardial damage at COVID-19

Author:

Hamidov S. H.1ORCID,Obrezan A. G.2ORCID,Lobanova P. S.3ORCID,Azarenko S. V.4ORCID

Affiliation:

1. Saint Petersburg State University; City Hospital № 40

2. Saint Petersburg State University; International Medical Centre “SOGAZ”

3. S. P. Botkin Saint Petersburg Infectious Diseases Hospital

4. Multi-field Clinic «Sestroretskaya

Abstract

   This work is devoted to a literature review of published articles, where studies are focused on studying the frequency, structure of complications of cardiovascular diseases in patients with COVID-19, that occurred in vivo and post-mortem: myocarditis, myocardial damage, AMI, and other thrombotic events. Some studies also provide comparative data on COVID-19+ and COVID-19- patients, complication patterns, and mortality rates. The results of the studied materials shows that, the frequency of cardiac complications and the number of deaths are significantly more common in patients with concomitant diseases such as arterial hypertension, diabetes mellitus, obesity, CKD, arrhythmias. Patients over 60 years of age are at increased risk of a severe course of the disease, this is due to the fact that these individuals have concomitant chronic diseases that are decompensated due to an acute infectious process, reducing the adaptive capabilities of the organism, and lead to a deterioration in survival rates.

Publisher

Intermedservice Ltd

Subject

General Medicine

Reference44 articles.

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2. Halushka M. K., Vander Heide R. S. Myocarditis is rare in COVID-19 autopsies: cardiovascular findings across 277 postmortem examinations. Cardiovasc Pathol. 2021; 50: 107300. PMID: 33132119. https://doi.org/10.1016/j.carpath.2020.107300

3. Blagova O. V. Otsenka urovnya antikardial'nykh antitel u bol'nykh s tyazhelym i srednetyazhelym techeniem COVID-19 (korrelyatsii s klinicheskoi kartinoi i prognozom) / O. V. Blagova [i dr.] // Rossiiskii kardiologicheskii zhurnal. – 2020. – 25 (11): 4054.. [Blagova O. V., Varionchik N. V., Zaydenov V. A., Savina P. O., Sarkisova N. D. Anticardiac antibodies in patients with severe and moderate COVID-19 (correlations with the clinical performance and prognosis). Russian Federationn Journal of Cardiology. 2020; 25 (11): 4054. (In Russ.)]. https://doi.org/10.15829/29/1560-4071-2020-4054

4. Chung, Mina K. et al. COVID-19 and Cardiovascular Disease: From Bench to Bedside. Circulation research vol. 128, 8 (2021): 1214-1236. https://doi.org/10.1161/CIRCRESAHA.121.317997

5. The CAPACITY-COVID Collaborative Consortium and LEOSS Study Group, Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries, European Heart Journal, 2021; ehab656. https://doi.org/10.1093/eurheartj/ehab656

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