The Latest Research Progress of Non-alcoholic Fatty Liver Disease-related Hepatocellular Carcinoma

Abstract

In modern society, with the improvement of people's living standards and the change of diet structure, non-alcoholic fatty liver disease (NAFLD) has become one of the most common chronic liver diseases worldwide. This disease seriously affects the quality of life of patients, and may also lead to serious complications such as cirrhosis and liver cancer, which brings heavy life burden to patients and their families. The incidence of hepatocellular carcinoma (HCC) in patients with NAFLD is significantly higher than that in patients without NAFLD. The risk of HCC in patients with NAFLD is closely related to the severity of fatty liver and the degree of liver fibrosis. The occurrence of HCC in patients with NAFLD is also related to metabolic diseases such as insulin resistance, obesity, and type 2 diabetes. This article focuses on the epidemiology, pathogenesis, early diagnosis and treatment of HCC.