The Effect of Treatment on Weight Gain in Iron Deficiency Anemia and Its Association with Ghrelin and Hepcidin Levels

Author:

KILINÇ Halil Cansun1ORCID,ÖNEÇ Birgül2ORCID,ONEC Kursad3ORCID,ANKARALI Handan4ORCID

Affiliation:

1. Department of Internal Medicine, Duzce University Faculty of Medicine

2. DÜZCE ÜNİVERSİTESİ, TIP FAKÜLTESİ

3. Department of Nephrology, Department of Internal Medicine, Duzce University Faculty of Medicine

4. İstanbul Medeniyet University, Faculty of Medicine, Department of Biostatistics and Medical Informatics

Abstract

Aim: Although loss of appetite in iron deficiency anemia (IDA) and weight gain during treatment are common complaints, there are very few studies in adults. This study aimed to determine the levels of ghrelin, one of the appetite-related hormones, and hepcidin, one of the main regulators of iron metabolism, in IDA, and to examine the effects of treatment on weight gain and the levels of these hormones. Material and Methods: Eighty-seven adult patients with IDA and a control group of 50 healthy volunteers were included in the study. Anthropometric measurements and blood samples were obtained from the patient and control groups before treatment, and repeated after treatment in the IDA group. Results: No significant difference was found in terms of weight, body mass index (BMI), and waist-to-hip ratio between groups but there was a significant increase in weight and BMI, in the patient group after treatment (both p

Funder

Düzce Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü

Publisher

Duzce Medical Journal

Subject

General Medicine

Reference33 articles.

1. World Health Organization (WHO). de Benoist B, McLean E, Egli I, Cogswell M, editors. Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia. Spain: WHO; 2008.

2. World Health Organization (WHO). Nutritional anaemias: report of a WHO scientific group. Geneva, Switzerland: WHO; 1968.

3. Turkish Society of Hematology. Erythrocyte diseases and hemoglobin disorders: diagnosis and treatment guidelines, version 1.3 - May 2022, İstanbul, Türkiye: Galenos Publishing House; 2022. Turkish.

4. Gereklioglu C, Asma S, Korur A, Erdogan F, Kut A. Medication adherence to oral iron therapy in patients with iron deficiency anemia. Pak J Med Sci. 2016;32(3):604-7.

5. Grumbach MM, Styne DM. Puberty: Ontogeny, neuroendocrinology, physiology, and disorders. In: Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, Wilson JD, Foster DW, editors. Williams textbook of endocrinology. 10th edition. Philadelphia: Saunders; 2003. p.1156.

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