Affiliation:
1. Aksaray Üniversitesi Tıp fakültesi
2. Sağlık Bilimleri Üniversitesi, Beyhekim Eğitim Araştırma Hastanesi, Konya
3. Özel MEDİTECH Hastanesi
Abstract
Aim: This study aimed to review cognitive function and fine motor skills in patients with multiple sclerosis (MS) and investigate the association with magnetic resonance imaging (MRI) results.
Material and Methods: The study included 22 patients diagnosed with relapsing-remitting MS and 22 controls. Participants underwent neuropsychological tests, including the Stroop test, Rey auditory verbal learning test (RAVLT), line bisection test (LBT), serial reaction time test (SRTT), and finger tapping test (FTT). The relationship between severity of disease, MRI, and test performance was investigated.
Results: It was determined that the patients were lateralized to the right in the LBT data, while the control group was lateralized to the left (p=0.024). On cognitive tests, there was no significant difference in Stroop test results (p=0.134), but the mean overall RAVLT of the patient group was significantly lower than that of the control group (p
Reference40 articles.
1. Ropper AH, Samuels MA. Adams and Victor’s principles of neurology. 9th ed. Translated by Emre M. Ankara: Güneş Medical Publishing House; 2011. p.874-903. Turkish.
2. Altıntaş A. Immunopathogenesis and pathology of multiple sclerosis. Turkiye Klinikleri J Neurol-Special Topics. 2009;2(2):1-8. Turkish.
3. Randall TS. Managing the symptoms of multiple sclerosis. 4th ed. New York: Demos Medical Publishing; 2006.
4. Mitchell AJ, Benito-Leon J, Gonzalez JM, Rivera-Navarro J. Quality of life and its assessment in multiple sclerosis: integrating physical and psychological components of wellbeing. Lancet Neurol. 2005;4(9):556-66.
5. Langdon DW. Cognition in multiple sclerosis. Curr Opin Neurol. 2011;24(3):244-9.