Characterization of a Catalytic Ligand Bridging Metal Ions in Phosphodiesterases 4 and 5 by Molecular Dynamics Simulations and Hybrid Quantum Mechanical/Molecular Mechanical Calculations
Author:
Publisher
Elsevier BV
Subject
Biophysics
Reference78 articles.
1. Cyclic nucleotide phosphodiesterases: relating structure and function;Francis;Prog. Nucleic Acid Res. Mol. Biol.,2001
2. Cyclic nucleotide phosphodiesterase 5 and sildenafil: Promises realized;Manganiello;Mol. Pharmacol.,2003
3. PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle;Karnam;Am. J. Physiol. Cell Physiol.,2002
4. Purification and properties of periplasmic 3′/5′-cyclic nucleotide phosphodiesterase—a novel zinc-containing enzyme from the marine symbiotic bacterium vibrio-fischeri;Callahan;J. Biol. Chem.,1995
5. Hormonal-regulation of cyclic-nucleotide phosphodiesterases;Conti;Endocr. Rev.,1991
Cited by 38 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Lifespan extension in Caenorhabditis elegans by oxyresveratrol supplementation in hyper-branched cyclodextrin-based nanosponges;International Journal of Pharmaceutics;2020-11
2. Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis;Nature Communications;2020-06-23
3. Structure and Regulation of EAL Domain Proteins;Microbial Cyclic Di-Nucleotide Signaling;2020
4. Discovery of 2‐(3,4‐dialkoxyphenyl)‐2‐(substituted pyridazin‐3‐yl)acetonitriles as phosphodiesterase 4 inhibitors with anti‐neuroinflammation potential based on three‐dimensional quantitative structure–activity relationship study;Chemical Biology & Drug Design;2018-12-26
5. Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings;European Journal of Medicinal Chemistry;2016-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3