Quantum and Molecular Dynamics Study for Binding of Macrocyclic Inhibitors to Human α-Thrombin
Author:
Publisher
Elsevier BV
Subject
Biophysics
Reference49 articles.
1. The coagulation cascade—initiation, maintenance, and regulation;Davie;Biochemistry,1991
2. Estimation of binding affinities for selective thrombin inhibitors via Monte Carlo simulations;Pierce;J. Med. Chem.,2001
3. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation;Vu;Cell,1991
4. Thrombin structure and function—why thrombin is the primary target for antithrombotics;Fenton;Blood Coagul. Fibrinolysis.,1991
5. Thrombotic complications of antithrombotic therapy: a paradox with implications for clinical practice;Raskob;Ann. Intern. Med.,1997
Cited by 44 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. (1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay;European Journal of Medicinal Chemistry;2022-11
2. Fragmentation-Based Decomposition of a Metalloenzyme–Substrate Interaction: A Case Study for a Lytic Polysaccharide Monooxygenase;The Journal of Physical Chemistry B;2022-07-14
3. Efficient synthesis and cytotoxic activity of polysubstituted thieno[2,3-d]pyrimidine derivatives;Journal of Molecular Structure;2022-05
4. Synthesis and anticancer activities of diverse furo[2,3-d]pyrimidine and benzofuro[3,2-d]pyrimidine derivatives;Synthetic Communications;2022-04-03
5. Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands;International Journal of Molecular Sciences;2021-10-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3