Heparin binding confers prion stability and impairs its aggregation

Author:

Vieira Tuane C. R. G.1,Cordeiro Yraima2,Caughey Byron3,Silva Jerson L.1

Affiliation:

1. Centro Nacional de Ressonância Magnética Nuclear Jiri JonasInstituto de Bioquímica Médica Leopoldo De MeisInstituto Nacional de Ciência e Tecnologia de Biologia Estrutural e BioimagemUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil

2. Faculdade de FarmáciaUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil

3. Laboratory of Persistent Viral Diseases, Rocky Mountain LaboratoriesNational Institute of Allergy and Infectious DiseasesU.S. National Institutes of HealthHamiltonMontanaUSA

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Cited by 57 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Prions;Molecular Medical Microbiology;2024

2. Extension of the SUGRES-1P Coarse-Grained Model of Polysaccharides to Heparin;Journal of Chemical Theory and Computation;2023-08-16

3. Full-length prion protein incorporated into prion aggregates is a marker for prion strain-specific destabilization of aggregate structure following cellular uptake;The Journal of Biochemistry;2023-04-26

4. Pharmacology of Heparin and Related Drugs: An Update;Pharmacological Reviews;2023-02-15

5. Prions;Encyclopedia of Cell Biology;2023

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