Fludarabine resistance mediated by aminoglycoside‐3'phosphotransferase‐IIa and the structurally related eukaryotic cAMP‐dependent protein kinase-Reference-Cited by-同舟云学术

Fludarabine resistance mediated by aminoglycoside‐3'phosphotransferase‐IIa and the structurally related eukaryotic cAMP‐dependent protein kinase

Published:2017-04-03 Issue:7 Volume:31 Page:3007-3017
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Sánchez‐Carrera Dámaso¹,Bravo‐Navas Sara¹,Cabezón Elena²,Arechaga Ignacio²,Cabezas Matilde²,Yáñez Lucrecia¹,Pipaón Carlos¹

Affiliation:

1. Laboratorio de Hematología MolecularServicio de Hematología y HemoterapiaHospital Universitario Marqués de Valdecilla–Instituto de Investigación Marqués de Valdecilla (IDIVAL)Santander Spain

2. Departamento de Biología Molecular and Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC)Universidad de Cantabria–Consejo Superior de Investigaciones Cientificas (CSIC)Santander Spain

Funder

Universitat de Barcelona

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201601245R

Reference32 articles.

1. Aminoglycoside phosphotransferases: proteins, structure, and mechanism

2. The Crystal Structure of Aminoglycoside-3′-Phosphotransferase-IIa, an Enzyme Responsible for Antibiotic Resistance

3. Fludarabine in the treatment of chronic lymphocytic leukemia: a review;Ricci F.;Ther. Clin. Risk Manag.,2009

4. Fludarabine inhibits DNA replication: a rationale for its use in the treatment of acute leukemias. Leuk;Gandhi V.;Lymphoma,1994

5. Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

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