Moderate alterations of the cytoskeleton in human chondrocytes after short‐term microgravity produced by parabolic flight maneuvers could be prevented by up‐regulation of BMP‐2 and SOX‐9-Reference-Cited by-同舟云学术

Moderate alterations of the cytoskeleton in human chondrocytes after short‐term microgravity produced by parabolic flight maneuvers could be prevented by up‐regulation of BMP‐2 and SOX‐9

Published:2015-02-13 Issue:6 Volume:29 Page:2303-2314
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Aleshcheva Ganna¹,Wehland Markus¹,Sahana Jayashree²,Bauer Johann³,Corydon Thomas J.²,Hemmersbach Ruth⁴,Frett Timo⁴,Egli Marcel⁵,Infanger Manfred¹,Grosse Jirka⁶,Grimm Daniela²

Affiliation:

1. Clinic for Plastic, Aesthetic and Hand SurgeryOtto‐von‐Guericke UniversityMagdeburgGermany

2. Department of BiomedicineAarhus UniversityAarhus CDenmark

3. Max‐Planck‐Institute for BiochemistryMartinsriedGermany

4. DLR German Aerospace CenterBiomedical Research, Gravitational BiologyCologneGermany

5. Aerospace Biomedical Science and Technology, Space Biology GroupLuzerne University of Applied Sciences and ArtsHergiswilSwitzerland

6. Department of Nuclear MedicineUniversity of RegensburgRegensburgGermany

Funder

European Space Agency

Aarhus Universitet

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.14-268151

Reference52 articles.

1. The study on the mechanical characteristics of articular cartilage in simulated microgravity

2. Greenwald E. Armstrong K. Leon P. Reinberger K.Understanding the physiological changes from microgravity.Growing cartilage in space. Available at:http://chen2820.pbworks.com/w/page/11951455/Growing%20cartilage%20in%20space Accessed February 10 2015

3. Microgravity: the immune response and bone

4. Neocartilage Formation in 1 g, Simulated, and Microgravity Environments: Implications for Tissue Engineering

5. The Effects of Weightlessness on the Human Organism and Mammalian Cells

Cited by 66 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring the Frontier of Space Medicine: The Nexus of Bone Regeneration and Astronautic Health in Microgravity Conditions;Microgravity Science and Technology;2024-09-02

2. Iguratimod suppresses sclerostin and receptor activator of NF-κB ligand production via the extracellular signal–regulated kinase/early growth response protein 1/tumor necrosis factor alpha pathway in osteocytes and ameliorates disuse osteoporosis in mice;Bone;2024-04

3. Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor;Biomolecules;2023-12-24

4. ACTB may serve as a predictive marker for the efficacy of lenvatinib in patients with HBV-related early-stage hepatocellular carcinoma following partial hepatectomy: a retrospective cohort study;Journal of Gastrointestinal Oncology;2023-12

5. Transcriptomic response of bioengineered human cartilage to parabolic flight microgravity is sex-dependent;npj Microgravity;2023-01-19