Monoacylglycerol lipase deficiency affects diet‐induced obesity, fat absorption, and feeding behavior in CB 1 cannabinoid receptor

Monoacylglycerol lipase deficiency affects diet‐induced obesity, fat absorption, and feeding behavior in CB 1 cannabinoid receptor–deficient mice

Published:2018-09-28 Issue:2 Volume:33 Page:2484-2497
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Yoshida Kenji¹,Kita Yoshihiro¹²,Tokuoka Suzumi M.¹,Hamano Fumie¹²³,Yamazaki Maya⁴⁵,Sakimura Kenji⁴,Kano Masanobu⁶⁷,Shimizu Takao¹³

Affiliation:

1. Department of LipidomicsThe University of TokyoTokyoJapan

2. Life Sciences Core FacilityThe University of TokyoTokyoJapan

3. Department of Lipid SignalingNational Center for Global Health and MedicineTokyoJapan

4. Department of Cellular NeurobiologyBrain Research InstituteNiigata UniversityNiigataJapan

5. Department of NeurologyUniversity of California, San FranciscoSan FranciscoCaliforniaUSA

6. Department of NeurophysiologyGraduate School of MedicineThe University of TokyoTokyoJapan

7. International Research Center for Neurointelligence (WPI-IRCN)University of Tokyo Institutes for Advanced Study (UTIAS)The University of TokyoTokyoJapan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Takeda Science Foundation

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201801203R

Reference53 articles.

1. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

2. Monoacylglycerol Lipase Activity Is a Critical Modulator of the Tone and Integrity of the Endocannabinoid System

3. Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

4. Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance

5. Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

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