Atorvastatin, but not pravastatin, inhibits cardiac Akt/mTOR signaling and disturbs mitochondrial ultrastructure in cardiac myocytes

Author:

Godoy Joseph C.1,Niesman Ingrid R.2,Busija Anna R.2,Kassan Adam123,Schilling Jan M.12,Schwarz Anna1,Alvarez Erika A.4,Dalton Nancy D.4,Drummond John C.12,Roth David M.12,Kararigas Georgios56,Patel Hemal H.12,Zemljic-Harpf Alice E.12

Affiliation:

1. Veterans Affairs San Diego Healthcare System San Diego California USA

2. Department of AnesthesiologyUniversity of California, San Diego La Jolla California USA

3. Department of Pharmaceutical SciencesSchool of PharmacyWest Coast University North Hollywood California USA

4. Department of MedicineUniversity of California, San Diego La Jolla California USA

5. Charité-Universitätsmedizin Berlin Berlin Germany

6. German Centre for Cardiovascular Research (DZHK) Berlin Germany

Funder

National Institutes of Health

National Heart, Lung, and Blood Institute

National Institute on Aging

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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