N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

Author:

Hofer Dina C.12,Zirkovits Gabriel1,Pelzmann Helmut J.13,Huber Katharina14,Pessentheiner Ariane R.15,Xia Wenmin1,Uno Kyosuke6,Miyazaki Toh6,Kon Kanta7,Tsuneki Hiroshi7,Pendl Tobias8,Al Zoughbi Wael9,Madreiter-Sokolowski Corina T.10,Trausinger Gert11,Abdellatif Mahmoud12,Schoiswohl Gabriele13,Schreiber Renate13,Eisenberg Tobias814,Magnes Christoph11,Sedej Simon1214,Eckhardt Matthias15,Sasahara Masakiyo16,Sasaoka Toshiyasu7,Nitta Atsumi6,Hoefler Gerald9,Graier Wolfgang F.1014,Kratky Dagmar1014,Auwerx Johan2,Bogner-Strauss Juliane G.114

Affiliation:

1. Institute of Biochemistry, Graz University of Technology, Graz, Austria;

2. Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland;

3. Fresenius Kabi Austria GmbH, Graz, Austria;

4. Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland;

5. Department of Medicine, University of California–San Diego, La Jolla, California, USA;

6. Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan;

7. Department of Clinical Pharmacology, University of Toyama, Toyama, Japan;

8. Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria;

9. Institute of Pathology, Medical University of Graz, Graz, Austria;

10. Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria;

11. Joanneum Research, HEALTH–Institute for Biomedicine and Health Sciences, Graz, Austria;

12. Department of Cardiology, Medical University of Graz, Graz, Austria;

13. Institute of Molecular Biosciences, University of Graz, Graz, Austria;

14. BioTechMed-Graz, Graz, Austria;

15. Institute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany

16. Department of Pathology, University of Toyama, Toyama, Japan

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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