Phospholipase Cβlb associates with a Shank3 complex at the cardiac sarcolemma
Author:
Affiliation:
1. Baker International Diabetes Institute (IDI) Heart and Diabetes Institute Melbourne Victoria Australia
2. Department of Pharmaceutical Sciences Oregon State University Corvallis Oregon USA
Funder
National Health and Medical Research Council
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.10-171470
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3. Gq‐initiated cardiomyocyte hypertrophy is mediated by phospholipase Cβ1b
4. The extreme C‐terminal region of phospholipase Cβ1 determines subcellular localization and function; the “b” splice variant mediates α1‐adrenergic receptor responses in cardiomyocytes
5. Selective activation of the “b” splice variant of phospholipase Cβ1 in chronically dilated human and mouse atria
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