Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

Author:

WIEMANN STEFANIE U.1,SATYANARAYANA ANDE1,TSAHURIDU MARTINA1,TILLMANN HANS L.1,ZENDER LARS1,KLEMPNAUER JUERGEN2,FLEMMING PEER3,FRANCO SONIA4,BLASCO MARIA A.4,MANNS MICHAEL P.1,RUDOLPH K. LENHARD1

Affiliation:

1. Department of Gastroenterology, Hepatology, and EndocrinologyMedical School Hannover Germany

2. Department of Visceral SurgeryMedical School Hannover Germany

3. Department of PathologyMedical School Hannover Germany

4. Department of Immunology and OncologyCentro National de Biotecnologia/CSIC Madrid Spain

Funder

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

Ministerio de Ciencia y Tecnología

European Commission

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference35 articles.

1. The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

2. Liver cirrhosis;Williams E. J.;Postgrad Med J,1998

3. Pathogenesis of Liver Fibrosis

4. Telomeres and telomerase in experimental liver cirrhosis;Rudolph K. L.;The Liver Biology and Pathobiology,2001

5. Structure and function of telomeres

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