Mitochondrial DNA 4977 bp deletion and OH 8 dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients-Reference-Cited by-同舟云学术

Mitochondrial DNA 4977 bp deletion and OH 8 dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients

Published:1999-06 Issue:9 Volume:13 Page:1083-1088
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Lezza Angela Maria Serena¹,Mecocci Patrizia²,Cormio Antonella¹,Real M. Flint³,Cherubini Antonio²,Cantatore Palmiro¹,Senin Umberto²,Gadaleta Maria Nicola¹

Affiliation:

1. Department of Biochemistry and Molecular BiologyUniversity of Bari70125BariItaly

2. Department of Gerontology and GeriatricsUniversity of Perugia06122PerugiaItaly

3. Neurology ResearchMGH Harvard Medical SchoolMassachusetts General HospitalBostonMassachusetts02114USA

Funder

Center for Neuroscience Research

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fasebj.13.9.1083

Reference34 articles.

1. DISEASES OF THE MITOCHONDRIAL DNA

2. Oxidative damage and mitochondrial decay in aging.

3. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

4. Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

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