Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS‐activator peroxynitrite-Reference-Cited by-同舟云学术

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Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS‐activator peroxynitrite

Published:2007-08-27 Issue:1 Volume:22 Page:215-224
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Schildknecht Stefan¹,Daiber Andreas²,Ghisla Sandro³,Cohen Richard A.¹,Bachschmid Markus M.¹

Affiliation:

1. Vascular Biology UnitWhitaker Cardiovascular InstituteBoston University School of MedicineBostonMassachusettsUSA

2. Department of CardiologyJohannes Gutenberg UniversityMainzGermany

3. Department of BiochemistryUniversity of KonstanzKonstanzGermany

Funder

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.06-8015com

Reference41 articles.

1. Pyrogen fever and prostaglandin-like activity in cerebrospinal fluid

2. Effect of pyrogen and antipyretics on prostaglandin activity in cisternal c.s.f. of unanaesthetized cats

3. Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

4. Structural insights into the stereochemistry of the cyclooxygenase reaction

5. Higher oxidation states of prostaglandin H synthase. Rapid electronic spectroscopy detected two spectral intermediates during the peroxidase reaction with prostaglandin G2

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