Lowering of tumor interstitial fluid pressure specifically augments efficacy of chemotherapy

Author:

Salnikov Alexei V.1,Iversen Vegard V.2,Koisti Markus3,Sundberg Christian1,Johansson Lars3,Stuhr Linda B.2,Sjöquist Mats4,Ahlström Håkan3,Reed Rolf K.2,Rubin Kristofer1

Affiliation:

1. Department of Medical Biochemistry and MicrobiologyUppsala University BMC, Box 582 SE-751 23 Uppsala Sweden

2. Department of PhysiologyUniversity of Bergen N-5009 Bergen Norway

3. Department of RadiologyUniversity Hospital SE-751 85 Uppsala Sweden

4. Department of Medical Cell Biology, Section of PhysiologyUppsala University BMC, Box 571 SE-751 23 Uppsala Sweden

Funder

Swedish Cancer Foundation

Norges Forskningsråd

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference34 articles.

1. Treatment of cancer with radiation and drugs.

2. The next frontier of molecular medicine: Delivery of therapeutics

3. Transvascular drug delivery in solid tumors;Yaun I.;Semin. Radiat. Oncol.,1998

4. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review;Vaupel P.;Cancer Res.,1989

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