Induced Cre‐mediated knockdown of Brca1 in skeletal muscle reduces mitochondrial respiration and prevents glucose intolerance in adult mice on a high‐fat diet

Author:

Jackson Kathryn C.1,Tarpey Michael D.2,Valencia Ana P.1,Iñigo Melissa R.12,Pratt Stephen J.3,Patteson Daniel J.2,McClung Joseph M.24,Lovering Richard M.3,Thomson David M.5,Spangenburg Espen E.124

Affiliation:

1. Department of KinesiologySchool of Public Health, University of Maryland College Park Maryland USA

2. Department of PhysiologyBrody School of MedicineEast Carolina University Greenville North Carolina USA

3. Department of OrthopaedicsSchool of Medicine, University of Maryland Baltimore Maryland USA

4. East Carolina Diabetes and Obesity InstituteEast Carolina University Greenville North Carolina USA

5. Department of Physiology and Developmental BiologyBrigham Young University Provo Utah USA

Funder

National Institutes of Health

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Heart, Lung, and Blood Institute

National Institute on Aging

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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