ATP‐sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT2 transporter regulate glucose‐stimulated insulin secretion

Author:

Liu Guo Jun1,Simpson Ann M.2,Swan M. Anne3,Tao Chang2,Tuch Bernard E.4,Crawford Russell M.5,Jovanovic Aleksandar5,Martin Donald K.16

Affiliation:

1. Department of Health SciencesUniversity of Technology Sydney Broadway N.S.W. Australia

2. Department of Cell and Molecular BiologyUniversity of Technology Sydney Broadway N.S.W. Australia

3. Department of Anatomy and HistologyInstitute for Biomedical Research, University of Sydney N.S.W. Australia

4. Diabetes Transplant UnitPrince of Wales Hospital, The University of New South Wales High St. Randwick N.S.W. Australia

5. Tayside Institute of Child Health, Ninewells Hospital and Medical School, University of Dundee Dundee Scotland, United Kingdom

6. Institute for Nanoscale Technology, University of Technology Sydney N.S.W. Australia

Funder

Diabetes Australia Research Trust

British Heart Foundation

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference34 articles.

1. Type I diabetes mellitus: a chronic autoimmune disease;Eisenbarth G. S.;N. Engl. J. Med.,1986

2. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

3. Functional expression of the human insulin gene in a human hepatoma cell line (HEPG2);Simpson A. M.;Gene Ther.,1995

4. Gene therapy of diabetes: glucose-stimulated insulin secretion in a human hepatoma cell line (HEP G2ins/g)

5. Secretion and storage of insulin from a human hepatoma cell line: Huh7-ins;Simpson A. M.;Transplant. Proc.,1999

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